[DESCRIPTION]
There is a towering stone wall with the words "Opioid Addiction" carved into it. Down at the bottom of the wall, there is a group of people who are living with opioid addiction.
[SPEECH]
Living with opioid addiction can be a struggle. Trapped in a cycle of opioid use, withdrawal, and cravings.
[DESCRIPTION]
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For adults whose withdrawal symptoms are controlled by oral buprenorphine for at least 7 days.
[SPEECH]
For adults with moderate to severe opioid addiction whose withdrawal symptoms are controlled by oral buprenorphine for at least 7 days, SUBLOCADE may help them keep moving towards recovery.
[DESCRIPTION]
On top of the wall, a man is leaving his house to walk his dog.
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SUBLOCADE® (buprenorphine extended-release) injection for subcutaneous use (CIII) 100mg-300mg
SUBLOCADE is available by prescription only.
[SPEECH]
In a study, people treated with once-monthly SUBLOCADE, plus counseling, were 14 times more likely to have treatment success versus placebo.
[DESCRIPTION]
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SUBLOCADE should be used with counseling.
Once-monthly plus counseling
14x more likely treatment success
28% of people on SUBLOCADE vs. 2% on placebo achieved treatment success defined as at least 80% weeks (not always consecutive) free of illicit opioids.
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SUBLOCADE continuously releases the medicine buprenorphine all month with no real daily ups and downs.
[DESCRIPTION]
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Continuously
Results may vary.
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Buprenorphine is known to reduce cravings and block the rewarding effects of opioids.
[DESCRIPTION]
The scene transitions to the man playing basketball at the gym with friends.
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Reduce cravings
Block rewarding effects
[SPEECH]
SUBLOCADE can cause serious life-threatening reactions and death if injected in a vein or if taken with certain other medicines or illicit drugs.
[DESCRIPTION]
The scene transitions to the man attending a group counseling meeting. He leaves the meeting to join an outdoor barbeque, taking place above the Opioid Addiction wall.
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SUBLOCADE can cause serious, life-threatening reactions and death if injected in a vein or if taken with certain other medicines or illicit drugs.
[SPEECH]
Do not take SUBLOCADE with other opioid medicines, benzodiazepines, alcohol, or other depressants without your doctor's approval.
Ask your doctor about naloxone for emergency treatment of opioid overdose. Get emergency help if naloxone is given, or if you feel faint, dizzy, confused, sleepy, uncoordinated, have blurred vision, slurred speech, or are breathing slower than normal. These can be signs of an overdose or other serious problems.
[DESCRIPTION]
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Buprenorphine is a controlled substance that can be abused. When taken by those not addicted to opioids, death has been reported.
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In an emergency, have family and friends tell medical staff you are physically dependent on opioids and are being treated with SUBLOCADE.
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The scene transitions to the man walking through the airport to meet his parents.
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The body can develop a dependence on SUBLOCADE, and can experience opioid withdrawal symptoms weeks or months after last dose.
[SPEECH]
This isn't a full list of risks and side effects. Talk to your doctor and read the patient labeling for more information. Don't give up. Ask a doctor if SUBLOCADE can help you keep moving towards recovery.
[DESCRIPTION]
The man leaves the airport and joins a group of people walking on top of the wall of Opioid Addiction. The scene pans out to show people above and below the wall. Everyone disappears, leaving only the wall of Opioid Addiction.
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For product information, call 1-877-782-6966 or visit SUBLOCADE.COM
Once-monthly SUBLOCADE®
Go to SUBLOCADE.COM for more information and product pricing.
Indivior®
INDICATION
SUBLOCADE® (buprenorphine extended-release) injection, for subcutaneous use, CIII, is a prescription medicine used to treat adults with moderate to severe addiction (dependence) to opioid drugs (prescription or illegal) who have received an oral transmucosal (used under the tongue or inside the cheek) buprenorphine-containing medicine at a dose that controls withdrawal symptoms for at least 7 days. SUBLOCADE is part of a complete treatment plan that should include counseling.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about SUBLOCADE?
Because of the serious risk of potential harm or death from self-injecting SUBLOCADE into a vein (intravenously), it is only available through a restricted program called the SUBLOCADE REMS Program.
SUBLOCADE contains an opioid medicine called buprenorphine that can cause serious and life-threatening breathing problems, especially if you take or use certain other medicines or drugs.
Talk to your healthcare provider about naloxone, a medicine available to patients for emergency treatment of an opioid overdose. If naloxone is given, you must call 911 or get emergency medical help right away to treat overdose or accidental use of an opioid.
SUBLOCADE may cause serious and life-threatening breathing problems. Get emergency help right away if you:
Do not take certain medicines during treatment with SUBLOCADE. Taking other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants (including street drugs) while on SUBLOCADE can cause severe drowsiness, decreased awareness, breathing problems, coma, and death.
Death has been reported in those who are not opioid dependent who received buprenorphine sublingually.
Who should not take SUBLOCADE?
Do not use SUBLOCADE if you are allergic to buprenorphine or any ingredient in the prefilled syringe (ATRIGEL® Delivery System, a biodegradable 50:50 poly(DL-lactide-co-glycolide) polymer and a biocompatible solvent, N-methyl-2-pyrrolidone (NMP)).
Before starting SUBLOCADE, tell your healthcare provider about all of your medical conditions, including if you have:
Tell your healthcare provider if you are:
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.
What should I avoid while being treated with SUBLOCADE?
What are the possible side effects of SUBLOCADE?
SUBLOCADE can cause serious side effects, including:
These are not all the possible side effects. Call your healthcare provider for medical advice about side effects.
To report pregnancy or side effects associated with taking SUBLOCADE, please call 1-877-782-6966. You are encouraged to report negative side effects of drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
For more information about SUBLOCADE, the full Prescribing Information including BOXED WARNING, and Medication Guide, visit www.sublocade.com or talk to your healthcare provider. For REMS information visit www.sublocadeREMS.com.
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SUBLOCADE is a registered trademark of Indivior UK Limited.
ATRIGEL is a registered trademark of Tolmar Therapeutics, Inc.
SUBLOCADE® is manufactured by Curia Global Inc., Albany, NY 12203.
Intended for US audiences.
© 2022 Indivior UK Limited | INDIVIOR is a registered trademark of Indivior UK Limited | All rights reserved.
P-BAG-US-01180