VIDEO TRANSCRIPT

[DESCRIPTION]

There is a towering stone wall with the words "Opioid Addiction" carved into it. Down at the bottom of the wall, there is a group of people who are living with opioid addiction.

[SPEECH]

Living with opioid addiction can be a struggle. Trapped in a cycle of opioid use, withdrawal, and cravings.

[DESCRIPTION]

On-screen text: For adults whose withdrawal symptoms are controlled by oral buprenorphine for at least 7 days.

[SPEECH]

For adults with moderate to severe opioid addiction whose withdrawal symptoms are controlled by oral buprenorphine for at least 7 days, SUBLOCADE may help them keep moving towards recovery.

[DESCRIPTION]

On top of the wall, a man is leaving his house to walk his dog.

On-screen text:

SUBLOCADE® (buprenorphine extended-release) injection for subcutaneous use (CIII) 100 mg-300 mg

SUBLOCADE is available by prescription only.

[SPEECH]

In a study, people treated with once-monthly SUBLOCADE, plus counseling, were 14 times more likely to have treatment success versus placebo.

[DESCRIPTION]

On-screen text:

Once-monthly plus counseling

SUBLOCADE should be used with counseling.

14x more likely treatment success

Continuously

28% of people on SUBLOCADE vs. 2% on placebo achieved treatment success defined as at least 80% weeks (not always consecutive) free of illicit opioids.

[SPEECH]

SUBLOCADE continuously releases the medicine buprenorphine all month with no real daily ups and downs.

[DESCRIPTION]

On-screen text: Results may vary.

[SPEECH]

Buprenorphine is known to reduce cravings and block the rewarding effects of opioids.

[DESCRIPTION]

The scene transitions to the man playing basketball at the gym with friends.

On-screen text:

Reduce cravings

Block rewarding effects

[SPEECH]

SUBLOCADE can cause serious life-treating reactions and death if injected in a vein or if taken with certain other medicines or illicit drugs.

[DESCRIPTION]

The scene transitions to the man attending a group counseling meeting. He leaves the meeting to join an outdoor barbeque, taking place above the Opioid Addiction wall.

On-screen text: SUBLOCADE can cause serious, life-threatening reactions and death if injected in a vein or if taken with certain other medicines or illicit drugs.

[SPEECH]

Tell your doctor if you are taking anxiety medicines, sleeping pills, tranquilizers, muscle relaxants, sedatives, antidepressants, antihistamines or drink alcohol.

Call your doctor right away or get emergency help if you feel faint, confused, very sleepy or very hot, are agitated, acting clumsy, breathing more slowly than normal or have stiff muscles. These can be signs of an overdose or other serious problems.

[DESCRIPTION]

The scene transitions to the man working in an office setting.

On-screen text: Buprenorphine is a controlled substance that can be abused. When taken by those not addicted to opioids, death has been reported.

[SPEECH]

In an emergency, have family members tell the emergency medical staff that you are physically dependent on opioids and are being treated with SUBLOCADE.

[DESCRIPTION]

The scene transitions to the man walking through the airport to meet his parents.

On-screen text: The body can develop a dependence on SUBLOCADE, and can experience opioid withdrawal symptoms weeks or months after last dose.

[SPEECH]

This is not a full list of risks and side effects. Talk to your doctor and read the patient labeling for more information. Don’t give up. Ask a doctor if SUBLOCADE can help you keep moving towards recovery.

[DESCRIPTION]

The man leaves the airport and joins a group of people walking on top of the wall of Opioid Addiction. The scene pans out to show people above and below the wall. Everyone disappears, leaving only the wall of Opioid Addiction.

On-screen text:

For product information, call 1-877-782-6966 or visit SUBLOCADE.com

Once-monthly SUBLOCADE®

Go to SUBLOCADE.com for more information and product pricing.

Indivior

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