Opioid addiction

Treating opioid addiction

Don’t give up. Opioid addiction can be treated.

If you’re thinking about treatment, you’ve already made a move towards recovery.

One approach, called medication-assisted treatment (MAT), is often recommended to help with long-term management.

What’s MAT?

MAT is a treatment that combines medication and counseling, because opioid addiction physically changes the brain, and affects behaviors and emotions. See the effects of opioid addiction on the brain.

According to the U.S. Department of Health and Human Services, for some people MAT is the most effective approach to treating opioid addiction.

Medication

Different medicines are used in MAT to address the physical part of opioid addiction.

Buprenorphine helps the brain get used to functioning without illicit opioids. Buprenorphine, at prescribed doses, is designed to have a weaker effect on the brain compared to illicit opioids and not cause a 'high'. Buprenorphine can help reduce cravings, while blocking the effects of other opioids. This can make other opioids less appealing.

Learn about SUBLOCADE, a medication that contains buprenorphine.

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Find a buprenorphine treatment provider

Counseling

Counseling can help people work on behaviors and emotions that may be linked to their addiction. In counseling, people may also identify things that trigger them to want to use opioids, like pain or stress, and learn to manage these things in healthy ways.

Remember, the job of a counselor is not meant to tell you what to do, but to help you learn skills to
problem-solve independently.

Talk to a healthcare provider if you need help finding counseling.

Thinking about treatment with SUBLOCADE?

SUBLOCADE continuously releases the medicine buprenorphine all month at sustained levels, with no real daily ups and downs. Learn about SUBLOCADE.

Whether you’ve tried to quit before or are thinking about it for the first time, you can get treated at any point. Don’t give up.

Download the SUBLOCADE Brochure

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IMPORTANT SAFETY INFORMATION AND INDICATION

What is the most important information I should know about SUBLOCADE?

Because of the serious risk of potential harm or death from self-injecting SUBLOCADE into a vein (intravenously), it is only available through a restricted program called the SUBLOCADE REMS Program.

In an emergency, you or your family should tell the emergency medical staff that you are physically dependent on an opioid and are being treated with SUBLOCADE.

Buprenorphine, the medicine in SUBLOCADE, can cause serious and life-threatening problems, especially if you take or use certain other medicines or drugs. Call your healthcare provider right away or get emergency help if you:

These can be signs of an overdose or other serious problems.

Death or serious harm, including life-threatening breathing problems, can happen if you take anxiety medicines or benzodiazepines, sleeping pills, tranquilizers, muscle relaxants, or sedatives, antidepressants, or antihistamines, or drink alcohol during treatment with SUBLOCADE. Tell your healthcare provider if you are taking any of these medicines and if you drink alcohol.

SUBLOCADE is a controlled substance (CIII) because it contains buprenorphine that can be a target for people who abuse prescription medicines or street drugs.

Death has been reported in those who are not opioid dependent who received buprenorphine sublingually.

Do not use SUBLOCADE if you are allergic to buprenorphine or any ingredient in the prefilled syringe (ATRIGEL® Delivery System, a biodegradable 50:50 poly(DL-lactide-co-glycolide) polymer and a biocompatible solvent, N-methyl-2-pyrrolidone (NMP)).

SUBLOCADE may not be right for you. Before starting SUBLOCADE, tell your healthcare provider about all of your medical conditions, including:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. SUBLOCADE may affect the way other medicines work and other medicines may affect how SUBLOCADE works. Some medicines may cause serious or life-threatening medical problems when taken with SUBLOCADE. Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist each time you get a new medicine.

The doses of certain medicines may need to be changed if used during treatment with SUBLOCADE. Do not take any medicine during treatment with SUBLOCADE until you have talked with your healthcare provider. Your healthcare provider will tell you if it is safe to take other medicines during treatment with SUBLOCADE.

You should not take anxiety medicines or benzodiazepines (such as Valium® or Xanax®), sleeping pills, tranquilizers, muscle relaxants, or sedatives (such as Ambien®), antidepressants, or antihistamines that are not prescribed to you during treatment with SUBLOCADE, as this can lead to slowed breathing, drowsiness, delayed reaction time, loss of consciousness or even death. If a healthcare provider is considering prescribing such a medicine for you, remind the healthcare provider that you are being treated with SUBLOCADE.

You may have detectable levels of SUBLOCADE in your body for a long period after stopping treatment with SUBLOCADE.

What should I avoid while being treated with SUBLOCADE?

What are the possible side effects of SUBLOCADE?

SUBLOCADE can cause serious side effects, including:

These symptoms may start weeks to months after your last dose of SUBLOCADE.

Your healthcare provider may do tests before and during treatment with SUBLOCADE to check your liver.

These are not all the possible side effects. Call your healthcare provider for medical advice about side effects.

To report pregnancy or side effects associated with taking SUBLOCADE, please call 1-877-782-6966. You are encouraged to report negative side effects of drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Indication

SUBLOCADE® (buprenorphine extended-release) injection, for subcutaneous use (CIII) is a prescription medicine used to treat adults with moderate to severe addiction (dependence) to opioid drugs (prescription or illegal) who have received an oral transmucosal (used under the tongue or inside the cheek) buprenorphine-containing medicine at a dose that controls withdrawal symptoms for at least 7 days. SUBLOCADE is part of a complete treatment plan that should include counseling.

For more information about SUBLOCADE, see the full Prescribing Information including BOXED WARNING, and Medication Guide or talk to your healthcare provider. For REMS information visit www.sublocadeREMS.com.