Opioid addiction

Treating opioid addiction

Don’t give up. Opioid addiction can be treated.

If you’re thinking about treatment, you’ve already made a move towards recovery.

One approach, called medication-assisted treatment (MAT), is often recommended to help with long-term management.

What’s MAT?

MAT is a treatment that combines medication and counseling, because opioid addiction physically changes the brain, and affects behaviors and emotions. See the effects of opioid addiction on the brain.

According to the U.S. Department of Health and Human Services, for some people MAT is the most effective approach to treating opioid addiction.


Different medicines are used in MAT to address opioid addiction.

Buprenorphine helps the brain get used to functioning without illicit opioids. Buprenorphine, at prescribed doses, is designed to have a weaker effect on the brain compared to illicit opioids and not cause a 'high'. Buprenorphine can help reduce cravings, while blocking the effects of other opioids. This can make other opioids less appealing.

Learn about SUBLOCADE, a medication that contains buprenorphine.

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Find a SUBLOCADE treatment provider

For more information on how to find a facility, call INSUPPORT® at 1-844-467-7778.


Counseling can help people work on behaviors and emotions that may be linked to their addiction. In counseling, people may also identify things that trigger them to want to use opioids, like pain or stress, and learn to manage these things in healthy ways.

Remember, the job of a counselor is not meant to tell you what to do, but to help you learn skills to
problem-solve independently.

Talk to a healthcare provider if you need help finding counseling.

Thinking about treatment with SUBLOCADE?

SUBLOCADE continuously releases the medicine buprenorphine all month at sustained levels, with no real daily ups and downs. Learn about SUBLOCADE.

Whether you’ve tried to quit before or are thinking about it for the first time, you can get treated at any point. Don’t give up.

Download the SUBLOCADE Brochure

Want information?

Find out more about opioid addiction and treating it.

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What is the most important information I should know about SUBLOCADE?

Because of the serious risk of potential harm or death from self-injecting SUBLOCADE into a vein (intravenously), it is only available through a restricted program called the SUBLOCADE REMS Program.

SUBLOCADE contains an opioid medicine called buprenorphine that can cause serious and life-threatening breathing problems, especially if you take or use certain other medicines or drugs.

Talk to your healthcare provider about naloxone, a medicine available to patients for emergency treatment of an opioid overdose. If naloxone is given, you must call 911 or get emergency medical help right away to treat overdose or accidental use of an opioid.

SUBLOCADE may cause serious and life‐threatening breathing problems. Get emergency help right away if you:

Do not take certain medicines during treatment with SUBLOCADE. Taking other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants (including street drugs) while on SUBLOCADE can cause severe drowsiness, decreased awareness, breathing problems, coma, and death.

Death has been reported in those who are not opioid dependent who received buprenorphine sublingually.

Who should not take SUBLOCADE?

Do not use SUBLOCADE if you are allergic to buprenorphine or any ingredient in the prefilled syringe (ATRIGEL® Delivery System, a biodegradable 50:50 poly(DL-lactide-co-glycolide) polymer and a biocompatible solvent, N-methyl-2-pyrrolidone (NMP)).

Before starting SUBLOCADE, tell your healthcare provider about all of your medical conditions, including if you have:

Tell your healthcare provider if you are:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

What should I avoid while being treated with SUBLOCADE?

What are the possible side effects of SUBLOCADE?

SUBLOCADE can cause serious side effects, including:

These are not all the possible side effects. Call your healthcare provider for medical advice about side effects.

To report pregnancy or side effects associated with taking SUBLOCADE, please call 1-877-782-6966. You are encouraged to report negative side effects of drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.


SUBLOCADE® (buprenorphine extended-release) injection, for subcutaneous use (CIII) is a prescription medicine used to treat adults with moderate to severe addiction (dependence) to opioid drugs (prescription or illegal) who have received an oral transmucosal (used under the tongue or inside the cheek) buprenorphine-containing medicine at a dose that controls withdrawal symptoms for at least 7 days. SUBLOCADE is part of a complete treatment plan that should include counseling.

For more information about SUBLOCADE, see the full Prescribing Information including BOXED WARNING, and Medication Guide or talk to your healthcare provider. For REMS information visit www.sublocadeREMS.com.